The victims, who were heading to Abuja in a newly launched Edo Line bus, were forced into the bush before operatives of the police arrived at the scene.
A viral video from the incident showed a long queue of vehicles parked on both sides of the expressway as panic spread among commuters.
Moses Iyamu, spokesperson of the Edo police command, confirmed the incident on Saturday, adding that 16 kidnap victims have been rescued.
“Sixteen of these passengers have been rescued safely while the rescue operation by Edo State Police in synergy with vigilantes and hunters continues,” he said.
Iyamu added that a search-and-rescue mission has been intensified to secure the release of the two passengers still in captivity.